Fire is one of the natural processes in grasslands that maintains an open canopy and creates discrete disturbances. Over time, the use of fire in the Great Plains has changed from traditional use by American Indians to suppression by European settlers to reintroduction by modern landowners and managers. Although there is a wealth of knowledge of plant and avian responses to fire in the Great Plains, responses are not as well understood for arthropods, including insects, spiders, and their close relatives. We conducted a review of the literature to synthesize research on arthropod responses to fire in the Great Plains. Our goal was to offer more insights to managers about how arthropods typically respond to fire and highlight areas that need more research.